The histopathological manifestation of the tattoo shows that the pigment particles are located at different depths of the dermis. The connective tissue around the shallow and middle dermis of the dermis is more common. A small number of lymphocytes and phagocytic cells containing pigment particles can also be seen.
Tattoos can cause local lesions, such as skin tuberculosis, suppurative diseases, or keloids, and basal cell carcinoma, squamous cell carcinoma, and melanoma have also been reported in the skin of the tattoo.
Tattoos can also cause allergic reactions locally, most commonly in mercury, chromium, and cobalt compounds. Dermatitis and tattoo granuloma occur. The latter's histopathological manifestation is sarcoidosis, and the tattoo particles are spread throughout the infiltration of the sarcoidosis reaction.
